A Human Genome Diversity Cell Line Panel

By H. Cann, C. de Toma, L. Cazes, Marie‐Fernande Legrand, Valérie Morel, L. Piouffre, J. Bodmer, W. Bodmer, B. Bonné-Tamir, A. Cambon-Thomsen and 31 more. Science, 2002

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Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/8957796f3dda32ca346c4d33d96545be6a414b73

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Citations in the corpus

Insights into human genetic variation and population history from 929 diverse genomes (2019, methodology): “The Human Genome Diversity Project (HGDP)– Centre d’Etude du Polymorphisme Humain (CEPH) panel (5) has constituted a key resource to which several iterations of genetic assays have been applied (3, 6–12).”
Discriminant analysis of principal components: a new method for the analysis of genetically structured populations (2010, positive): “These results Figure 6 Inference of the number of clusters in the extended HGDP-CEPH data.”
New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree. (2008, background): “While the original set of 74 Y Chromosome Consortium (2002) cell lines is no longer available for this purpose, we suggest that typing of the current markers on the widely available CEPH-HGDP panel (Cann et al. 2002) would be a highly desirable goal for a future study.”
Genetics in geographically structured populations: defining, estimating and interpreting FST (2009, background): “10) cannot reflect differences in migration rate because both estimates are derived from the same set of individuals and the same set of populations — the Human Genome Diversity Project–Centre d'Etude du Polymorphisme Humain sampl”
Variants in nicotinic receptors and risk for nicotine dependence. (2008, background): “org To assess the frequency of the minor allele (A) at rs16969968 across multiple populations, this SNP was successfully typed in the Human Genome Diversity Cell Line Panel, which included 995 individuals representing 39 different populations (23).”
Exome sequencing reveals VCP mutations as a cause of familial ALS (2010, neutral): “An additional series of 364 anonymous African and Asian samples that are part of the HGDP (Cann et al., 2002) were included in the mutational analysis as controls to evaluate the genetic variability of VCP in non-Caucasian populations.”
Ancestry informative markers for fine-scale individual assignment to worldwide populations (2010, background): “a collection of samples including more than 1000 individuals from 51 populations from around the world,”
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD (2011, background): “In this paper, we used next-generation sequencing technology to identify a hexanucleotide repeat expansion within the C9ORF72 gene as the cause of chromosome 9p21-linked s (n = 478). eral European (non-Finnish) descent (n = 268). pean descent (n = 409) and Human Gene Diversity Panel 7–268, October 2”
Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children (2016, methodology): “Amish and Hutterite genotypes were projected onto the sample space created by Human Genome Diversity Project (HGDP) for European populations.(15) Panel B shows endotoxin levels in airborne dust from 10 Amish and 10 Hutterite homes.”
Ancient Admixture in Human History (2012, methodology): “We genotyped 934 unrelated individuals from the HGDP (Cann et al. 2002) and here report the value of f3-statistics on either SNPs ascertained as a heterozygote in a single HGDP San individual, or at SNPs ascertained in a single Han Chinese (Table 6).”
The 'Out of Africa' Hypothesis, Human Genetic Diversity, and Comparative Economic Development (2013, neutral): “…overall genetic diversity, H exp , as (6) H exp = 1 − 1 _ m ∑ l=1 m ∑ i=1 k l p i 2 , where k l is the number of observed variants in locus l. 16 For a more detailed description of the HGDP-CEPH Human Genome Diversity Cell Line Panel dataset, the interested reader is referred to Cann et al. (2002).”
Informativeness of genetic markers for inference of ancestry. (2003, background): “…set of 377 microsatellite markers—45 dinucleotides, 58 trinucleotides , and 274 tetranucleotides—genotyped in 1,056 individuals from 52 human populations (Cann et al. 2002; Rosenberg et al. 2002; Zhivotovsky et al. 2003; Human Diversity Panel Genotypes Web site; Human STRP Screening Sets Web site).”