New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree.

By T. Karafet, F. Mendez, Monica B. Meilerman, P. Underhill, S. Zegura, M. Hammer. Genome Research, 2008

868 citations recorded by the source corpus.

Markers on the non-recombining portion of the human Y chromosome continue to have applications in many fields including evolutionary biology, forensics, medical genetics, and genealogical reconstruction. In 2002, the Y Chromosome Consortium published a single parsimony tree showing the relationships among 153 haplogroups based on 243 binary markers and devised a standardized nomenclature system to name lineages nested within this tree. Here we present an extensively revised Y chromosome tree containing 311 distinct haplogroups, including two new major haplogroups (S and T), and incorporating approximately 600 binary markers. We describe major changes in the topology of the parsimony tree and provide names for new and rearranged lineages within the tree following the rules presented by the Y Chromosome Consortium in 2002. Several changes in the tree topology have important implications for studies of human ancestry. We also present demography-independent age estimates for 11 of the major clades in the new Y chromosome tree.

Subfields: Genetics, Plant Science

View Paper: https://www.semanticscholar.org/paper/10f44b458d7379dfef6dbae8ffae3f09a52f6b36

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Citations in the corpus

• Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation (2009, background): “Recently, an updated haplogroup tree of the patrilineally inherited, non-recombining part of the human Y chromosome (NRY) was published (Karafet et al., 2008).”