Reversal of obesity by targeted ablation of adipose tissue

By M. Kolonin, P. Saha, L. Chan, R. Pasqualini, W. Arap. Nature Medicine, 2004

599 citations recorded by the source corpus.

How researchers see this paper

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The growing problem of obesity in dogs and cats. (2006, unknown): “Human obesity is associated with an increased risk of type II DM, cancer, cardiac disease, hypertension, and decreased longevity (32).”
Hypoxia-Inducible Factor 1α Induces Fibrosis and Insulin Resistance in White Adipose Tissue (2009, background): “These metabolic improvements are somewhat surprising, considering that the forced reduction of fat mass in the context of lipodystrophies leads to a decrease rather than an increase in systemic insulin sensitivity (30, 36).”
Phage display technology: applications and innovations (2005, background): “Perhaps the most striking and promising contribution of in vivo use of phage display comes with the work of Kolonin and colleagues, who recently published a study in which a fat-targeting peptide was used to cure high-calorie related obesity in living animals (Kolonin et al. 2004).”
What We Talk About When We Talk About Fat (2014, unknown): “This strategy reduces body weight and improves glucose homeostasis in both rodents and nonhuman primates (Barnhart et al., 2011; Kim et al., 2012; Kolonin et al., 2004).”