Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex

By T. Pizzorusso, P. Medini, N. Berardi, Sabrina Chierzi, J. Fawcett, L. Maffei. Science, 2002

1,677 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Ophthalmology

View Paper: https://www.semanticscholar.org/paper/892efe565e964fa1435e16b1ea7751c754b1c3a6

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In Cellular and Molecular Neuroscience

In Ophthalmology

Takao K. Hensch

Citations in the corpus

Plasticity of the visual cortex and treatment of amblyopia. (2014, neutral): “ocular dominance plasticity [30] and even promote recovery from long-term monocular deprivation [31].”
Adolescence as a neurobiological critical period for the development of higher-order cognition (2018, positive): “, 2010)—which can result in excessive, unnecessary, and inefficient restructuring of circuit architecture—and the degradation of PNNs can reinstate CP plasticity (Pizzorusso et al., 2002) suggesting that PNNs play an important role in braking CP development.”
Sensitive Periods in the Development of the Brain and Behavior (2004, background): “For example, ocular dominance plasticity in the visual cortex has been increased in adult cats or rats by injecting fetal astrocytes, enzymatically degrading extracellular matrix proteoglycans, or by raising levels of BDNF, NE, or ACh (Huberman & McAllister, 2002; Pizzorusso et al., 2002; Lein & Sha”
Critical period plasticity in local cortical circuits (2005, background): “, and ocular dominance shifts can once again be induced by monocular deprivation, even in adulthoo”
Critical period regulation. (2004, background): “Degradation of these structures by repeated local chondroitinase injection reveals shifts of responsiveness toward the open eye following MD in adult rats (Pizzorusso et al. 2002).”
Learning rules and persistence of dendritic spines (2010, background): “The critical period reopens when extracellular matrix proteins are removed (Pizzorusso et al., 2002; Mataga et al., 2004).”
The Role of Microglia in the Healthy Brain (2011, background): “Both factors have been shown to promote dendritic spine motility and pruning, as well as experiencedependent plasticity in vitro and in vivo (Pizzorusso et al., 2002; Mataga et al., 2004; Oray et al., 2006).”
Common circuit defect of excitatory-inhibitory balance in mouse models of autism (2009, positive): “3), the administration of chondrotinases to remove peri-neuronal nets that preferentially enwrap mature PV-basket cells may be effective [17].”