Immunogenic cell death in cancer therapy.

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STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors (2014, background): “It is worth contrasting the STING-dependent mechanism we have observed as critical for spontaneous T cell priming against tumors with mechanistic data regarding immunogenic cell death induced by certain chemotherapeutic agents (Kroemer et al., 2013).”
ROS and the DNA damage response in cancer (2018, neutral): “to eventual T-cell mediated killing [116].”
Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. (2013, background): “In contrast to this dogma, however, some instances of apoptosis—such as those induced by radiotherapy and some chemotherapeutics—appears to bemore efficient than necrosis—as induced by freeze-thawing or osmotic lysis—at eliciting tumor-specific adaptive immune responses, reflecting the fact that the”
Cold Tumors: A Therapeutic Challenge for Immunotherapy (2019, background): “The absence or low production of DAMPs could induce a lack of DCs maturation as well as production of immunosuppressive factors such as transforming growth factor beta (TGF-β) leading to the absence of CD4 T cell help (30, 31).”