An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

By G. Wayman, M. Davare, Hideaki Ando, D. Fortin, O. Varlamova, H. M. Cheng, D. Marks, K. Obrietan, T. Soderling, R. Goodman and 1 more. Proceedings of the National Academy of Sciences of the United States of America, 2008

594 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/880a849cda98e80978d1dffc62846f4939f33bce

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In Molecular Biology

1. Paul L. Greer
2. Michael E. Greenberg

Citations in the corpus

• Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. (2010, unknown): “…miRNAs We asked which target genes might mediate the bidirectional effects of miR-125b and miR-132 on synaptic physiology. shRNA-mediated knockdown of the known miR-132 target p250GAP was recently found to increase dendritic spine size (Nakazawa et al., 2008; Vo et al., 2005; Wayman et al., 2008).”
• From synapse to nucleus: calcium-dependent gene transcription in the control of synapse development and function. (2008, background): “Overexpression of miRNA132 increases, while blocking miRNA132 function decreases, neurite growth (Vo et al., 2005). miRNA132 controls dendritic growth by regulating the translation of p250GAP, a protein that affects actin cytoskeletal dynamics (Wayman et al., 2008a).”
• Calmodulin-Kinases: Modulators of Neuronal Development and Plasticity (2008, unknown): “…for CaMKK/CaMKI in regulation of axonal growth cone morphology/motility and axonal outgrowth (Wayman et al., 2004), dendritic arborization (Takemoto-Kimura et al., 2007; Wayman et al., 2006, 2008), and formation of dendritic spines and synapses (Saneyoshi et al., 2008) (Figures 3 and 4).”