Platelet-Derived Serotonin Mediates Liver Regeneration

By M. Lesurtel, R. Graf, B. Aleil, D. Walther, Yinghua Tian, W. Jochum, C. Gachet, M. Bader, P. Clavien. Science, 2006

792 citations recorded by the source corpus.

Subfields: Hepatology, Surgery

View Paper: https://www.semanticscholar.org/paper/87f34328e84d26c1b6b1884e00c4d02317c4fd20

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In Hepatology

1. G. Michalopoulos

In Surgery

1. G. Michalopoulos

Citations in the corpus

• Psychedelics (2016, background): “Platelets are major carriers of serotonin in the blood, and 5-HT2A/2C serotonin agonist DOI completely restored liver proliferation in thrombocytopenic mice (Lesurtel et al., 2006). Partial (70%) hepatectomy was performed in mice, in which platelet function was inhibited pharmacologically or platele”
• The Expanded Biology of Serotonin (2009, positive): “In particular, platelet-derived serotonin signals through 5-HT2A and 5-HT2B receptors to promote liver regeneration (57).”
• Liver regeneration (2007, background): “Also increasing in circulation are the concentrations of TNF (Yamada et al., 1998), bile acids (Huang et al., 2006), IL6 (Cressman et al., 1996), and serotonin (Lesurtel et al., 2006).”