Evaluation of liver diffusion isotropy and characterization of focal hepatic lesions with two single-shot echo-planar MR imaging sequences: prospective study in 66 patients.

By B. Taouli, V. Vilgrain, E. Dumont, J. Daire, B. Fan, Y. Menu. Radiology, 2003

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What can we see with IVIM MRI? (2017, neutral): “Still, IVIM/diffusion MRI for assessing hepatic lesions is challenging, as there is sometimes an overlap between benign and malignant lesions and normal liver tissue (Anderson et al., 2014; Taouli et al., 2003; Koh et al., 2006).”
Diffusion-weighted MRI in the body: applications and challenges in oncology. (2007, background): “For example, although some researchers have reported that metastases have lower ADC values than liver [31], others have found the ADCs of metastases to be higher than that of liver [34, 35].”
Diffusion-weighted magnetic resonance imaging as a cancer biomarker: consensus and recommendations. (2009, background): “Diffusion-weighted MRI is able to differentiate between benign and malignant focal hepatic lesions in many cases based on the higher ADC of benign lesions compared with malignant lesions [22].”