Induction and mechanism of action of transforming growth factor‐β‐secreting Th3 regulatory cells

By Howard L. Weiner. Immunological Reviews, 2001

990 citations recorded by the source corpus.

Subfields: Immunology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/864a9b24919a3e7533a61cb7dfb15f2770d990fc

How researchers see this paper

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In Immunology

1. A. O’Garra
2. C. Hawrylowicz
3. M. Cho
4. M. Viguier
5. Louis Dubertret
6. F. Lemaître
7. P. Kourilsky
8. H. Bachelez

In Immunology and Allergy

1. M. Cho
2. M. Viguier
3. Louis Dubertret
4. F. Lemaître
5. P. Kourilsky
6. H. Bachelez
7. L. Ferradini
8. O. Vérola

Citations in the corpus

• Foxp3 Expressing CD4+CD25high Regulatory T Cells Are Overrepresented in Human Metastatic Melanoma Lymph Nodes and Inhibit the Function of Infiltrating T Cells1 (2004, methodology): “Our data suggest that Tr1/Th3-like T cells (22, 23) secreting both IL-10 and TGF- could be detected in melanoma metastatic LNs among CD4 CD25 T cells.”
• Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. (2005, background): “We further demonstrate that drug-induced IL-10–secreting Tregs are distinct for TGF-β synthesizing Th3 cells, as they show no increased synthesis of TGF-β, and neutralizing antibody to this cytokine does not modify their inhibitory function (17).”