Development of broad virus resistance in non-transgenic cucumber using CRISPR/Cas9 technology.

By J. Chandrasekaran, M. Brumin, D. Wolf, D. Leibman, C. Klap, M. Pearlsman, A. Sherman, T. Arazi, A. Gal‐On. Molecular plant pathology, 2016

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CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture. (2019, background): “With regard to viral diseases, use of CRISPR/Cas9 has also produced tungro disease–resistant eif4g rice (102), broad potyvirus–resistant eif4e cucumber (15), and cotton leaf curl disease–resistant clcud cotton (47).”
Seed Transmission of Tobamoviruses: Aspects of Global Disease Distribution (2017, methodology): “Successful application of the Cas9 methodology was reported for the virus genera: Geminivirus [116], Potyvirus, and Ipomovirus [117].”
Genome Editing—Principles and Applications for Functional Genomics Research and Crop Improvement (2017, background): “The eukaryotic translation initiation factor eIF4E is a host factor required by plant RNA viruses to maintain their life cycle and mutations in this gene have produced broad virus resistance in T3 non-transgenic cucumbers (Chandrasekaran et al., 2016).”