BDNF in schizophrenia, depression and corresponding animal models

By F. Angelucci, S. Brené, A. Mathé. Molecular Psychiatry, 2005

598 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression (2009, background): “Significant decreases in neurotrophins, particularly brain-derived neurotrophic factor (BDNF), have been detected in depression and in stress-induced animal models of depression (Angelucci et al. 2005; Smith et al. 1995).”
Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior (2012, background): “Several neurotrophic factors are also involved in the development and maturation of cholinergic neurons, but the dependence on neurotrophins is not homogenous throughout the CNS (for reviews, see Angelucci et al., 2005 and Schindowski et al., 2008).”
EPIGENETIC REGULATION OF BDNF GENE TRANSCRIPTION IN THE CONSOLIDATION OF FEAR MEMORY (2008, background): “Importantly, aberrant bdnf gene expression has also been specifically implicated in the etiology of several of these mental illnesses, including schizophrenia, depression, and bipolar disorder (Weickert et al., 2003; Angelucci et al., 2005; Tsankova et al., 2007).”