Antimicrobial peptides: linking partition, activity and high membrane-bound concentrations

By M. Melo, R. Ferré, Miguel A. R. B. Castanho. Nature Reviews Microbiology, 2009

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Insights into Cronobacter sakazakii Biofilm Formation and Control Strategies in the Food Industry (2020, background): “AMPs can be classified into four types based on secondary structure—namely, b-sheet, a-helical, loop, and extended peptide—with the first two classes being the most common in nature [108].”
Antimicrobial peptides: key components of the innate immune system (2012, background): “Prior to formation of both barrelstave and toroidal pores, the peptide adsorbs parallel to the membrane surface (Huang, 2006; Huang, 2009; Melo et al., 2009).”
Designing antimicrobial peptides: form follows function (2011, background): “Some natural AMPs, like porcine protegrin, exhibit strong antimicrobial effects but in general the activity of AMPs is improved by their increased concentrations in phagocyte granules, the crypts of the intestine and near degranulating phagocytes 15–17 .”