Staphylococcus aureus Capsular Polysaccharides

By K. O'Riordan, Jean C. Lee. Clinical Microbiology Reviews, 2004

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Reduced Vancomycin Susceptibility in Staphylococcus aureus, Including Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Strains: Resistance Mechanisms, Laboratory Detection, and Clinical Implications (2010, neutral): “Also of relevance here are the transcriptional profiles of VSSA and VISA strains exposed to vancomycin and other cell wall-active antibiotics (168, 199, 202, 361, 392) or when cell TABLE 3—Continued Isolate studied Phenotype (vancomycin MIC g/ml ) Isolate description Phenotypic feature(s) of hVISA o”
Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues (2009, background): “Nucleotide sequences of the cap5 gene cluster comprise a 16-gene operon (capA-P) and two of its products, CapP and CapO, function as epimerase and dehydrogenase in the synthesis UDP-N-acetylmannosaminuronic acid (UDP-ManNAcA) (27, 28).”
Teichoic acids and related cell-wall glycopolymers in Gram-positive physiology and host interactions (2008, background): “Alternatively, in the absence of additional protective layers, such as the capsul”
Pathogenesis of methicillin-resistant Staphylococcus aureus infection. (2008, background): “The zwitterionic capsule (both positively and negatively charged) can also induce abscess formation [17, 18].”