The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.
By Alexander G Baltz, Mathias Munschauer, Björn Schwanhäusser, Alexandra Vasile, Y. Murakawa, M. Schueler, Noah Youngs, D. Penfold-Brown, K. Drew, M. Milek and 5 more. Molecules and Cells, 2012
1,214 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/141b7bd385613ec170e04d6e9adac6e053434737
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Chuan He
- Zhike Lu
- Qing Dai
- Xiu-Jie Wang
- Anireddy S. N. Reddy
- Thomas Tuschl
- Andrea Barta
- Matthias W. Hentze
Citations in the corpus
- Comprehensive Identification of RNA-Binding Domains in Human Cells (2016, methodology): “Due to their different specificities, each protease also contributes unique 1% FDR RBDpeps to the complete peptide superset (Figure S1G), covering 529 RBPs that highly overlap with human RNA interactomes (Figure 1G) (Baltz et al., 2012; Beckmann et al., 2015; Castello et al., 2012).”
- ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility (2012, positive): “ysis, 492 of these DEGs were enriched in functional pathways related to RNA metabolic processes (Figure 4 and Table S3), consistent with the functional analysis performed on the published PAR-CLIP result of ALKBH5 in HEK293 cells (Baltz et al., 2012) that RNA metabolism is one of the most enriched f”
- A census of human RNA-binding proteins (2014, background): “Independent of my own studies, two proteome-wide pulldown studies of RBPs also isolated FAM98A (Baltz et al., 2012; Castello et al., 2012) and one study verified its binding”
- Complexity of the Alternative Splicing Landscape in Plants[C][W][OPEN] (2013, background): “These studies suggest the functional significance of AS as a result of tandem acceptor in plants.”
- N6-methyl-adenosine (m6A) in RNA: An Old Modification with A Novel Epigenetic Function (2012, background): “A photocrosslinkingbased mRNA-bound proteomics analysis has identified ALKBH5 to be an mRNA-binding protein [59], which is consistent with our finding of ALKBH5 as demethylase of m(6)A in mRNA [26].”