The biology and function of exosomes in cancer.

By Raghu Kalluri. Journal of Clinical Investigation, 2016

1,566 citations recorded by the source corpus.

Subfields: Cancer Research, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/114832b2ac2cee6c5da3d2d062fdb4bad5bd4386

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Rakesh K. Jain
2. N. Ferrara
3. Dai Fukumura
4. Peter Carmeliet
5. R. Kerbel
6. Lance L. Munn
7. K. Alitalo
8. G. Bergers

In Infectious Diseases

1. C. Hughes
2. Raghu Kalluri

In Molecular Biology

1. Rakesh K. Jain
2. N. Ferrara
3. Peter Carmeliet
4. Dai Fukumura
5. K. Alitalo
6. J. Joyce
7. R. Kerbel
8. Lance L. Munn

Citations in the corpus

• Exosome-Based Cell-Cell Communication in the Tumor Microenvironment (2018, background): “, 2013), exosomes are small EVs, ranging in size from 30 to 150 nm, with a multivesicular endosomal origin actively secreted by all cell types upon fusion of Multivesicular Bodies with the plasma membrane (Becker et al., 2016; Kalluri, 2016).”
• Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy. (2018, background): “Exosomes are 40- to 150-nm extracellular vesicles (EVs) of endosomal origin and are secreted by all cell types [7,8].”
• Extracellular Vesicle Heterogeneity: Subpopulations, Isolation Techniques, and Diverse Functions in Cancer Progression (2018, background): “In terms of pathophysiological processes, EVs have established as important players in diseases such as cancer (7), neurodegenerative disease (8), and viral infection (9).”
• Exosomes maintain cellular homeostasis by excreting harmful DNA from cells (2017, neutral): “Pools of exosomes are packed in the MVEs and released into the extracellular space after the fusion of MVEs with the plasma membrane 18,21,22 .”
• The biology, function, and biomedical applications of exosomes (2020, neutral): “Cancer The study of exosomes in cancer has progressed at a rapid pace comparedwith research into their role in other diseases (2, 145), and exosomes have been associated with several hallmark features of cancer (146).”
• Consensus guidelines for the use and interpretation of angiogenesis assays (2018, background): “They have gained considerable attention recently as they allow to study tumor features through a so-called liquid biopsy approach [267, 268].”