The Marine Viromes of Four Oceanic Regions

By Florent E. Angly, B. Felts, Mya Breitbart, Peter Salamon, Robert A. Edwards, C. Carlson, A. M. Chan, Matthew Haynes, S. Kelley, Hong Liu and 8 more. PLoS Biology, 2006

931 citations recorded by the source corpus.

Viruses are the most common biological entities in the marine environment. There has not been a global survey of these viruses, and consequently, it is not known what types of viruses are in Earth's oceans or how they are distributed. Metagenomic analyses of 184 viral assemblages collected over a decade and representing 68 sites in four major oceanic regions showed that most of the viral sequences were not similar to those in the current databases. There was a distinct “marine-ness” quality to the viral assemblages. Global diversity was very high, presumably several hundred thousand of species, and regional richness varied on a North-South latitudinal gradient. The marine regions had different assemblages of viruses. Cyanophages and a newly discovered clade of single-stranded DNA phages dominated the Sargasso Sea sample, whereas prophage-like sequences were most common in the Arctic. However most viral species were found to be widespread. With a majority of shared species between oceanic regions, most of the differences between viral assemblages seemed to be explained by variation in the occurrence of the most common viral species and not by exclusion of different viral genomes. These results support the idea that viruses are widely dispersed and that local environmental conditions enrich for certain viral types through selective pressure.

Subfields: Ecology, Epidemiology

View Paper: https://www.semanticscholar.org/paper/8383ced972f9209c614bbccdb3f8360659d26d60

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology

In Epidemiology

Citations in the corpus

The Messinian Salinity Crisis from mega-deposits to microbiology – A consensus report (2008, methodology): “This approach had not been previously used to obtain large fragments of DNA from environmental halophages and represents an alternative for shotgun cloning (Breitbart et al., 2002; Breitbart et al., 2003; Angly et al., 2006), a technique that has reported lots of data about the uncultured “metavirom”
CRISPRTarget (2013, background): “33 The lack of identified crRNA targets in plasmids results from a similar dearth of sequence data relative to the their abundance and diversity.”
Exploring the Vast Diversity of Marine Viruses (2007, background): “Furthermore, 65–95% of marine viral metagenomic sequences are not simi- lar to previously described sequences (Breitbart et al., 2002, 2004; Angly et al., 2006; Culley et al., 2006), as opposed to ~ 10% for cellular metagenomic surveys (Tyson et al., 2004; Venter et al., 2004), suggesting that we…”
Next‐generation sequencing technologies for environmental DNA research (2012, neutral): “Marine viromes were also investigated by Angly et al. (2006).”
Viruses manipulate the marine environment (2009, background): “Marine viral metagenomes, or 'viromes', collected from across the world have shown that viral species are globally distributed (everything is everywhere) but that the relative abundance of each species is restricted by local selectio”
CAMERA: A Community Resource for Metagenomics (2007, methodology): “…publications [2–4]; metagenome data from the Hawaii Ocean Time Series Station ALOHA [5] and marine viromes from four different oceanic regions[6]; standard nonredundant sequence databases (e.g., nrnt for nucleotides and nraa for amino acids[7]); and collections of microbial genome sequences,…”
Viriobenthos in freshwater and marine sediments : a review (2008, background): “The diversity of viruses in aquatic ecosystems is also impressive: metagenomic analyses indicate that 3000–7000 genetically distinct genomes can occur in 200 L of water (Breitbart et al., 2004; Angly et al., 2006).”