Macrophage ABCA1 and ABCG1, but not SR-BI, promote macrophage reverse cholesterol transport in vivo.

By Xun Wang, H. Collins, M. Ranalletta, I. Fuki, J. Billheimer, G. Rothblat, A. Tall, D. Rader. Journal of Clinical Investigation, 2007

613 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/82c0e22bf37a291addacafcc746407f67243364a

How researchers see this paper

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In Molecular Biology

1. Jonathan C. Cohen
2. Xiaochun Li
3. Helen H. Hobbs
4. Xiaofeng Qi
5. Elina Ikonen

In Oncology

1. Elina Ikonen

In Surgery

1. Jonathan C. Cohen
2. Helen H. Hobbs
3. Elina Ikonen

Citations in the corpus

• HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms (2011, background): “Although SRB1 is important in removing esterified cholesterol from the circulation and transporting it to the liver, it is not critical for exporting cholesterol from macrophages”
• Molecular basis of cholesterol efflux via ABCG subfamily transporters (2021, background): “G1 has been reported to facilitate reverse cholesterol transport (16, 17), the pathway by which cholesterol made in peripheral tissues is transported back to the liver or to the gut for excretion (18).”
• Cellular cholesterol trafficking and compartmentalization (2008, background): “Instead, scavenger receptor B1 ( SRB1 ), which can also facilitate cholesterol efflux to HDL, did not promote macrophage cholesterol efflux in vivo”