Signal Transduction and the Control of Gene Expression

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Histone Modifications at Human Enhancers Reflect Global Cell Type-Specific Gene Expression (2009, background): “STAT1 generally binds its target DNA sequences only after IFN-c induction 20 , with a small frac-tionofbindingpossiblebeforeinduction 21 .”
Identifying sources of variation and the flow of information in biochemical networks (2012, neutral): “þEf−V 1⁄2ZjH1$ þ V 1⁄2Z$g: [14]”
Transcription factors as targets for cancer therapy (2002, background): “The second group of transcription factors that were recognized to have a role in cancer are resident nuclear proteins, which are activated by serine kinase cascade”
Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes (2002, background): “, a family of transcription factors known to transduce TGF-β signal”
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor (2004, background): “, and tested the biochemical state of the components of the major signaling pathway”