G Protein-Coupled Receptors in Anopheles gambiae

By C. Hill, A. Fox, R. Pitts, Lauren B. Kent, P. L. Tan, M. A. Chrystal, A. Cravchik, F. S. Collins, Hugh M. Robertson, L. Zwiebel. Science, 2002

690 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Genetics, Insect Science

View Paper: https://www.semanticscholar.org/paper/7f55e539c28c06ae44e7d94983ba3ad46fe47e01

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

In Genetics

In Insect Science

Citations in the corpus

Anatomical profiling of G protein-coupled receptor expression (2008, neutral): “Although in vivo roles have been defined for many of the approximately 370 nonodorant GPCRs in mice and humans, the expression and function of many such receptors are incompletely characterized, and a significant fraction remain orphans (Fredriksson et al., 2003; Fredriksson and Schioth, 2005; Hill ”
Assessment of pollen rewards by foraging bees (2017, background): “…fewer than found in other insects [60 genes encoding 68 receptor proteins in fruit flies (Liman, Zhang & Montell 2014); 52 genes for 76 receptors in mosquitoes (Hill et al. 2002)], and has been taken as an indication of bees’ limited ability to detect gustatory compounds in their environment.”
The chemoreceptor superfamily in the honey bee, Apis mellifera: expansion of the odorant, but not gustatory, receptor family. (2006, background): “gambiae repertoire of 76 Grs encoded by 52 genes (Hill et al. 2002).”
Complementary Function and Integrated Wiring of the Evolutionarily Distinct Drosophila Olfactory Subsystems (2011, background): “…contrast to OR repertoires, which are highly divergent across even phylogenetically close families of insects, such as fruit flies and mosquitoes (Hill et al., 2002), the deeper conservation of IRs offers a possibility to consider how the stepwise expansion of this receptor repertoire during…”
Plant essential oils and formamidines as insecticides/acaricides: what are the molecular targets? (2011, background): “Therefore, arthropod tyramine and octopamine receptors might emerge as promising targets for insecticides/acaricides (e.g., plant essential oil components) with no or low toxicity in vertebrates.”
Molecular architecture of smell and taste in Drosophila. (2007, background): “The recent availability of the complete genome of the malaria mosquito, Anopheles gambiae, has opened up the possibility of studying the molecular basis of olfaction in this deadly insect (Fox et al. 2001, Hill et al. 2002).”
3.15 – Molecular Basis of Pheromone Detection in Insects (2005, background): “…Nomenclature Committee, 2000; Hill et al., 2002; Vosshall, 2003a), and another 69 candidate gustatory receptor genes (GR) (Dgr) a few of which are also likely involved in odor detection (Clyne et al., 2000; Dunipace et al., 2001; Scott et al., 2001; Hill et al., 2002); all appear to be GPCRs.”
Amino acid coevolution reveals three-dimensional structure and functional domains of insect odorant receptors (2015, critical): “Thus, the shared heptahelical secondary structure of these receptor families is, in contrast to initial assumptions 8, 9 , likely to be coincidental and not necessarily indicative of a shared signalling mechanism.”
Olfaction: diverse species, conserved principles. (2005, neutral): “…Niimura and Nei, 2003; (2) Gilad et al., 2005; (3) Gilad et al., 2004; (4) Young et al., 2003; (5) Rat Genome Sequencing Project Consortium, 2004; (6) Quignon et al., 2003; (7) Freitag et al., 1998; (8) Niimura and Nei, 2005; (9) Robertson et al., 2003; (10) Hill et al., 2002; (11) Robertson, 2001.”