Oxidative stress and regulation of glutathione in lung inflammation.

By I. Rahman, W. Macnee. European Respiratory Journal, 2000

941 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/7f48ecffe4be138c501a42fd27b7cf24ac0fe774

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. V. Lushchak
2. M. Kampa
3. E. Castanas

In Molecular Biology

1. V. Lushchak
2. A. Choi
3. M. Kampa
4. E. Castanas
5. H. Sies

Citations in the corpus

• Human health effects of air pollution. (2008, background): “Common cellular mechanism by which most air pollutants exert their adverse effects is their ability to act directly as prooxidants of lipids and proteins or as free radicals generators, promoting oxidative stress and the induction of inflammatory responses (Menzel, 1994; Rahman and MacNee, 2000).”
• Heme oxygenase-1: from bench to bedside. (2005, background): “Glutathione presents a first line of defense against oxidants in the lung; when glutathione is depleted, HO-1 expression is increased, suggesting a complimentary defensive role against oxidative stress (114,115).”
• Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions (2012, background): “Upregulation of this process provides an additional mechanism for GSH maintenance in the cell.”