Xenogeneic extracellular matrix as a scaffold for tissue reconstruction.

By S. Badylak. Transplant Immunology, 2004

761 citations recorded by the source corpus.

Subfields: Biomaterials, Surgery

View Paper: https://www.semanticscholar.org/paper/7f03fb9a80e9a68a20145f81030baf4131bc548c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. A. Atala
2. G. Lozier
3. Sergio Rodriguez
4. Pedro M. Baptista
5. M. Siddiqui
6. S. Soker
7. B. Brown
8. R. Gauvin

In Surgery

1. S. Badylak
2. B. Brown
3. B. Chan
4. A. Atala
5. S. Soker
6. G. Lozier
7. Sergio Rodriguez
8. Pedro M. Baptista

Citations in the corpus

• Macrophage phenotype as a predictor of constructive remodeling following the implantation of biologically derived surgical mesh materials. (2012, background): “Biologic materials composed of extracellular matrix (ECM) have been harvested from a wide variety of tissues and organs and have been used in a similarly wide variety of preclinical and clinical applications [1, 2].”
• Scaffolding in tissue engineering: general approaches and tissue-specific considerations (2008, background): “Specialized decellularization techniques are developed to remove cellular components and this is usually achieved by a combination of physical, chemical and enzymatic methods [9, 40].”
• The use of whole organ decellularization for the generation of a vascularized liver organoid (2011, methodology): “Previously, decellularization of tissue was performed by submersion of the tissue within a detergent solution under agitation to allow cell removal in bulk from the surface of the tissue moving inward.(24) These approaches were successful for decellularization of smaller samples (up to 5 mm in thick”
• Macrophage phenotype and remodeling outcomes in response to biologic scaffolds with and without a cellular component. (2009, background): “multiple forms of allogeneic and xenogeneic ECM from sources such as small intestine, urinary bladder, and skin have been investigated as biologic scaffolds for tissue reconstruction in both preclinical studies and human clinical applications [4,5].”
• Collagen-Based Biomaterials for Tissue Engineering Applications (2010, background): “Thus, acellular ECM are typically produced from human or porcine dermis or from swine intestine or bladder submucosa (SIS or BSM) [26].”
• Properties of the amniotic membrane for potential use in tissue engineering. (2008, methodology): “For example, methods of chemically cross-linking the ECM for purposes of increased material strength and slower in vivo degradation have uniformly resulted in a scaffold material that is less biocompatible than ECM that is preserved in its native state (Badylak, 2004).”