Collagen-Based Biomaterials for Tissue Engineering Applications

By R. Parenteau-Bareil, R. Gauvin, F. Berthod. Materials, 2010

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Collagen is the most widely distributed class of proteins in the human body. The use of collagen-based biomaterials in the field of tissue engineering applications has been intensively growing over the past decades. Multiple cross-linking methods were investigated and different combinations with other biopolymers were explored in order to improve tissue function. Collagen possesses a major advantage in being biodegradable, biocompatible, easily available and highly versatile. However, since collagen is a protein, it remains difficult to sterilize without alterations to its structure. This review presents a comprehensive overview of the various applications of collagen-based biomaterials developed for tissue engineering, aimed at providing a functional material for use in regenerative medicine from the laboratory bench to the patient bedside.

Subfields: Biomaterials, Surgery

View Paper: https://www.semanticscholar.org/paper/5486ece5156acac6f87c0a0391b2b21ad9b1d2de

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