Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

By K. Yoon, Seung-Hyun Ko, Jae-Hyoung Cho, Jung Min Lee, Y. Ahn, K. Song, S. Yoo, M. Kang, B. Cha, K. Lee and 5 more. 2003

609 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Genetics, Surgery

View Paper: https://www.semanticscholar.org/paper/7eabd0d3caf098e96bd76b255913fd793a2c8d6d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. J. Henquin
2. M. Cnop
3. B. Wajchenberg
4. Decio L. Eizirik

In Genetics

1. M. Cnop
2. F. Ortis
3. J. Henquin
4. B. Wajchenberg
5. Decio L. Eizirik

In Surgery

1. M. Cnop
2. F. Ortis
3. J. Henquin
4. B. Wajchenberg
5. Decio L. Eizirik

Citations in the corpus

• Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia. (2008, methodology): “Pancreatic insulin was extracted by a previously published method (Yoon et al., 2003).”
• Pancreatic β‐cell mass in European subjects with type 2 diabetes (2008, background): “On average, this decrease amounted to 30–50% of normal in postmortem morphological comparisons of pancreatic samples from non-diabetic and type 2 diabetic subjects [3–7].”
• Initiation and execution of lipotoxic ER stress in pancreatic β-cells (2008, background): “This element functions as a binding site for both XBP1 (Yoshida et al., 2001) and ATF6 (Wang et al., 2000).”
• Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis. (2008, background): “pears to be an important contributory factor (6, 9, 10).”
• beta-cell failure in diabetes and preservation by clinical treatment. (2007, background): “Regarding GLP-1, DPP-IV activation results in the inactivation of GLP-1 (7-36) amide and the generation of the metabolite GLP-1 (9-36) amide, which did not activate the GLP-1 receptor, thus not enhancing the insulin secretion and not blocking GLP-1 (7-36) amide enhancement of insulin secretion durin”
• A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure (2016, neutral): “Otherwise, the variation in the ratio of alpha cells to beta cells falls within the expected range (Fadista et al., 2014; Yoon et al., 2003).”