A perspective of polyamine metabolism.

By H. Wallace, A. Fraser, Alun D. Hughes. Biochemical Journal, 2003

944 citations recorded by the source corpus.

Subfields: Biochemistry, Molecular Biology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/7e1ba10556dc48a192557f8d859507f972211250

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. Carol A. Colton

In Molecular Biology

1. Thomas Berberich
2. C. Stasolla
3. Carol A. Colton
4. K. Baron
5. R. Casero

Citations in the corpus

• Polyamines: essential factors for growth and survival (2008, background): “In addition to these suggested transport mechanisms that also act as control points for the adjustment of intracellular polyamine levels, two additional mammalian mechanisms have also been proposed (Wallace et al. 2003).”
• Cadmium-induced oxidative damage in rice leaves is reduced by polyamines (2007, background): “that polyamines are involved in a number of cellular and molecular processes in plants (Bouchereau et al. 1999; Wallace et al. 2003).”
• Targeting polyamine metabolism and function in cancer and other hyperproliferative diseases (2007, background): “Development of polyamine analogues Although the targeted inhibition of specific biosynthetic enzymes in the polyamine metabolic pathway has yet to have significant clinical success in the treatment of cancer, there is a large body of data that substantiate polyamine function and metabolism as rat”
• Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain (2009, background): “Polyamines (putrescine, spermidine, and spermine) are multivalent cations essential for cell proliferation and differentiation (Thomas and Thomas 2001; Wallace et al. 1981; Wallace et al. 2003).”
• The role of polyamines during in vivo and in vitro development (2008, background): “Polyamines are low-molecular-weight, aliphatic, polycationic compounds carrying positive charges on nitrogen atoms, a property which facilitates electrostatic interactions with macromolecules such as DNA, RNA, phospholipids, cell wall components, and proteins (Wallace et al. 2003).”
• Chilling tolerance in Nicotiana tabacum induced by seed priming with putrescine (2011, background): “The concentration of Spd and Spm was less improved than Put by exogenous Put treatments, because Spd and Spm might be produced from Put according to the synthesis way of PAs (Wallace et al. 2003).”