Polymorphisms associated with cholesterol and risk of cardiovascular events.
By Sekar Kathiresan, O. Melander, D. Anevski, C. Guiducci, N. Burtt, C. Roos, Joel Hirschhorn, G. Berglund, B. Hedblad, Leif Groop and 3 more. New England Journal of Medicine, 2008
738 citations recorded by the source corpus.
Subfields: Endocrinology, Diabetes and Metabolism, Genetics, Surgery
View Paper: https://www.semanticscholar.org/paper/7e03c948e8aac8bc5d5741f91f8938f808144071
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Endocrinology, Diabetes and Metabolism
In Genetics
- Gonçalo R. Abecasis
- Mark J. Daly
- Cristen J. Willer
- Yun Li
- Serena Sanna
- David Altshuler
- Yurii S. Aulchenko
- Eric Boerwinkle
In Surgery
- Sekar Kathiresan
- Mark J. Daly
- David Altshuler
- E. Ding
- R. Collins
- Børge G. Nordestgaard
- I. Graham
- Massimo F. Piepoli
Citations in the corpus
- Genetically elevated lipoprotein(a) and increased risk of myocardial infarction. (2009, neutral): “Participants in the 1991-1994 examination by age, y 21-46 (n = 2204) 52 (48-55) 27 (25-30) 16 (14-18) 12 (11-13)”
- Testing for an Unusual Distribution of Rare Variants (2011, background): “have a substantial effect on serum low-density lipoprotein cholesterol (LDL-C) [1], these variants influence risk or protection to myocardial infarction by only a factor of 2 [2,3].”
- Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study (2008, methodology): “Finally, we assigned identical risk to each allele in creating the genetic risk score for ease of interpretation, as done previously (47).”
- 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. (2010, neutral): “002) in a model including he genotype score (90).”
- Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study (2012, methodology): “Additionally, through resequencing, we identifi ed a loss-of-function coding SNP at the endothelial lipase gene (LIPG Asn396Ser) that aff ects plasma HDL cholesterol in isolation.(18,19) Here, we use these SNPs in case-control studies and prospective cohort studies to test the hypothesis that geneti”
- Common variants at 30 loci contribute to polygenic dyslipidemia (2008, background): “As lipid genotypes have been shown to add incremental information beyond plasma lipoprotein measurement”
- Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts (2008, background): “In contrast to rare variants with major effects such as those underlying familial hypercholesterolemia, common variants improve the prediction of cardiovascular disease only marginally in terms of the clinical classification of patient”
- Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease (2016, neutral): “0 or 1 healthy lifestyle factor 2193 (28) 3,321 (16) 4,945 (22) 1098 (26)”