C-reactive protein: a critical update.

By M. B. Pepys, Gideon M. Hirschfield. Journal of Clinical Investigation, 2003

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Current concepts in the diagnosis and management of cytokine release syndrome. (2014, positive): “CRP is an acute phase reactant produced by the liver largely in response to IL-6, and CRP levels serve as a reliable surrogate for IL-6 bioactivity.(38,39) During CRS, CRP can increase by several logs, and this assay is rapid, inexpensive, and readily available in most hospitals.”
Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions. (2010, background): “However, these direct actions in cell culture have been questioned in recent years (Pepys and Hirschfield, 2003).”
The role of defective clearance of apoptotic cells in systemic autoimmunity (2010, background): “CRP binds to the membranes of damaged cells, to phospholipids and to small nuclear ribonucleoproteins”
Effects of infection and inflammation on lipid and lipoprotein metabolism: mechanisms and consequences to the host. (2004, neutral): “residues of phospholipids or microbial products (260).”
Subcutaneous and visceral adipose tissue: structural and functional differences (2010, neutral): “VAT is more infiltrated with inflammatory cells and is more capable of generating those proteins than SCAT (4,32,33).”
Research Progress on the Relationship between Atherosclerosis and Inflammation (2018, background): “The native circulating form of CRP is pentameric (pCRP), which is mostly released into the circulation after inflammatory stimuli [16].”