B7-H4, a molecule of the B7 family, negatively regulates T cell immunity.

By G. Sica, I. Choi, G. Zhu, K. Tamada, Shengxi Wang, H. Tamura, A. Chapoval, D. Flies, Jürgen Bajorath, Lieping Chen. Immunity, 2003

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Immunosuppressive networks in the tumour environment and their therapeutic relevance (2005, background): “B7-H4 was shown to be a negative regulator of T-cell responses in vitro by inhibiting T-cell proliferation, cell-cycle progression and cytokine productio”
B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma (2006, background): “Antigen-specifi c T cell responses are impaired in mice treated with a B7-H4Ig fusion protein (22).”
Inhibitory B7-family molecules in the tumour microenvironment (2008, background): “B7-H4 was also identified by DNA sequence homology to other B7 molecule”
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator (2005, background): “There has been an indirect indication that the B7 family member B7x (also identified as B7S1 and B7-H4”
Co-inhibitory molecules of the B7–CD28 family in the control of T-cell immunity (2004, background): “Emerging co-inhibitors: B7-H4 and BTLA B7-H4 (B7S1, B7X) is a recently identified B7-family member with co-inhibitory functio”