Decreased Bacterial Diversity Characterizes an Altered Gut Microbiota in Psoriatic Arthritis and Resembles Dysbiosis of Inflammatory Bowel Disease
By J. Scher, C. Ubeda, A. Artacho, M. Attur, Sandrine Isaac, Soumya M. Reddy, Shoshana Marmon, A. Neimann, Samuel B. Brusca, T. Patel and 4 more. Arthritis & Rheumatology, 2015
729 citations recorded by the source corpus.
To characterize the diversity and taxonomic relative abundance of the gut microbiota in patients with never‐treated, recent‐onset psoriatic arthritis (PsA).
Subfields: Dermatology, Molecular Biology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/7bfacf8c15b7cb252d000cea7797d1bca9296910
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
Citations in the corpus
- Gut Microbiota and Immune System Interactions (2020, background): “Although studies to date have failed to reveal a single etiological pathogenic species responsible for IBD, the current view is that while individual species may play significant roles in immunomodulation, collateral damage to the gut microbiota due to their loss or overabundance plays a key role in”
- Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism (2016, background): “A similar loss of diversity has been observed in other auto-immune pathologies, such as psioaritic arthritis, suggesting a role for the microbiota and its metabolites in immune regulation.(23) Insight into the links between diversity and function are also observed in interventions that have profound”
- Impact of the Gut Microbiota on Intestinal Immunity Mediated by Tryptophan Metabolism (2018, background): “Based on the close relationship observed between SpA and intestinal inflammation, the microbiota has been suggested to be a potential factor in influencing immune responsiveness in SpA patients (Fantini, 2009; Scher et al., 2015).”