Shift of whispering-gallery modes in microspheres by protein adsorption.

By Stephen Arnold, M. Khoshsima, I. Teraoka, S. Holler, F. Vollmer. Optics Letters, 2003

752 citations recorded by the source corpus.

Subfields: Atomic and Molecular Physics, and Optics, Electrical and Electronic Engineering

View Paper: https://www.semanticscholar.org/paper/7be0e5629016e0c5ce2e51e325aabefe7e4001ec

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In Atomic and Molecular Physics, and Optics

In Electrical and Electronic Engineering

Citations in the corpus

Sparse Regularization via Convex Analysis (2017, methodology): “This data was acquired using a whispering gallery mode (WGM) sensor designed to detect nano-particles with high sensitivity [3], [21].”
Whispering gallery mode sensors (2015, background): “For the case of the homogenous and random binding of a biomolecule such as protein or DNA onto the surface of a microsphere resonator, we find that the resonance wavelength shift δλ of a fundamental WGM is related to the surface concentration csurf of the adsorbed species by [150,293,294]”
Optical detection of single non-absorbing molecules using the surface plasmon resonance of a gold nanorod. (2012, background): “Metal nanoparticles [5, 6] or dielectric resonators [7, 8, 9] detect non-absorbing molecules by a resonance shift in response to a local perturbation of the refractive index, but neither has reached single-protein sensitivity.”
Single virus detection from the reactive shift of a whispering-gallery mode (2008, background): “By dividing the shift in frequency by the single photon energy –h r on the left and by the volume integral of the associated electromagnetic energy density on the right, we arrive at a simple expression for the fractional frequency shift (2),”
Overview of novel integrated optical ring resonator bio/chemical sensors (2007, methodology): “(3) by matching the boundary ~ 10 0 μm W G M”
Ligand–receptor interaction platforms and their applications for drug discovery (2012, background): “The resonant recirculation of light within a microcavity allows the light to sample the analyte molecules many times [98-101].”
On the performance quantification of resonant refractive index sensors. (2008, background): “For biomolecule detection applications, the specific capture of biomolecules at the sensor surface results in a local change in RI, producing a sensing signal that enables quantification of the biomolecules in the sample [3,6,11,12,14].”
Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation (2010, background): “To address these issues, researchers have turned to waveguide-based, monolithically integrated resonant interferometers, such as Bragg-grating-based Fabry–Perot resonators [6], microspheres [7], [8], microdisks [9], [10], microtoroids [11], photonic crystal cavities [12], and ring resonators [13]–[1”