How Clonal Is Staphylococcus aureus?

By E. Feil, J. Cooper, H. Grundmann, D. Robinson, M. Enright, T. Berendt, S. Peacock, John M Smith, M. Murphy, B. Spratt and 2 more. Journal of Bacteriology, 2003

652 citations recorded by the source corpus.

Subfields: Infectious Diseases, Microbiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/7bb658710265bf79845afc9dbfa46df710412138

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Citations in the corpus

A Field Guide to Pandemic, Epidemic and Sporadic Clones of Methicillin-Resistant Staphylococcus aureus (2011, methodology): “According to MLST data, CC188 is related to CC1 although it differs in two alleles (arcC-3 and gmk-8 instead of arcC-1 and gmk-1 [169]).”
Multi-locus sequence typing: a tool for global epidemiology. (2003, background): “In several cases limited diversity of the bacterial population makes assignment of isolates to clonal complexes relatively straightforward [ 14 ].”
Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins (2014, background): “Staphylococcus aureus is considered to be a predominantly clonally-evolving species, based on the rarity with which MLST loci were observed to be exchanged between representatives (57) and the low level of homoplasy in the S.”
eBURST: Inferring Patterns of Evolutionary Descent among Clusters of Related Bacterial Genotypes from Multilocus Sequence Typing Data (2004, methodology): “We demonstrate the utility of this approach by using MLST data from antibiotic-resistant Streptococcus pneumoniae (8, 35) and from Staphylococcus aureus (9, 11, 16), Campylobacter jejuni (7, 31, 34), and Neisseria meningitidis (20, 23).”
Community-Associated Methicillin-Resistant Staphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic (2010, background): “Abundant molecular evidence supports the hypothesis that CA-MRSA clones have arisen in the community by the horizontal transfer of SCCmec elements and PVL genes, molecular features commonly associated with CA-MRSA isolates as well as perhaps other virulence and resistance factors, to the genomes of ”
Pulsed-Field Gel Electrophoresis Typing of Oxacillin-Resistant Staphylococcus aureus Isolates from the United States: Establishing a National Database (2003, background): “aureus and those with health care-associated infections (21).”
The Population Genetics of dN/dS (2008, background): “This observation holds for bacterial data [11,12,14,16,18], for viral samples isolated from a single host versus viral samples isolated from different hosts [13], for closely related viral samples versus distantly diverged samples [48], and for conspecific versus interspecific mammalian sequences [4”
SRST2: Rapid genomic surveillance for public health and hospital microbiology labs (2014, methodology): “were forward evolved under the coalescent, using the parameters of the best-fitting model for each locus, mutation rate 1E-7 and recombination rate 1E-7/15 (based on reported r/m of 1/15 [46]).”
Methicillin-Resistant Staphylococcus aureus: Molecular Characterization, Evolution, and Epidemiology (2018, background): “In 2003 Feil et al, (290) estimated the rate of recombination within clonal complexes and concluded that the specific alleles and individual nucleotides are more prone to mutation, being at least 15-fold more likely to change by point mutation than by recombination.”
Three-year surveillance of community-acquired Staphylococcus aureus infections in children. (2005, background): “Physicians caring for children throughout the United States and the world are likely to face the same problem with CA-MRSA that we have described in this report, as the USA300 or other CA-MRSA clones are introduced into their communities.”
Marine bacterial microdiversity as revealed by internal transcribed spacer analysis (2005, background): “…discerning molecular analysis (e.g. multilocus sequence typing [MLST] or ITS analysis) of cultured isolates has demonstrated that many bacterial ‘species’ consist of numerous ‘ecotypes’, often with identical or near identical 16S rRNA gene sequences (e.g. Rocap et al. 2002, Feil et al. 2003).”
Typing of Methicillin-Resistant Staphylococcus aureus in a University Hospital Setting by Using Novel Software for spa Repeat Determination and Database Management (2003, background): “…of the high cost and the necessity of access to a high-throughput DNA sequencing facility Although there is evidence for recombination in S . aureus (10), it has been shown that point mutations by far exceed recombination events, in contrast to N . meningitidis or Streptococcus pneumoniae (11 .”