Molecular aspects of the early stages of elicitation of secondary metabolites in plants

By A. Vasconsuelo, R. Boland. 2007

375 citations recorded by the source corpus.

Plants are a source of commercially important secondary metabolites. Elicitation of plant cells in culture represents a useful biotechnological tool to improve the production of these valuable metabolites. Greater knowledge on the mechanism of elicitation has basic as well as practical implications. This review summarizes molecular information available about the early stages of the elicitation process and the mode of action of elicitors. A description is first provided on the importance of plant secondary metabolism, its induction by elicitation, the elicitor concept and classification, factors affecting elicitation and the mechanisms involved, with a major emphasis on the intracellular transduction systems which mediate the actions of elicitors, namely, elicitor receptors, GTP binding proteins, the Ca2+ messenger system and the PI3K, PLC/IP3-DAG/PKC and adenylyl cyclase/cAMP/PKA pathways, which finally act through mitogen-activated protein kinases (MAPKs) affecting the expression of genes related to the biosynthesis of secondary metabolites. Relevant experimental approaches used to study these topics are also discussed.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/7b59ce180820dc61e4a81d73d4f655e94beaca9e

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Citations in the corpus

Stress Protective Role of Secondary Metabolites Diversity of Functions and Mechanisms (2008, positive): “The large diversity of chemical types and interactions displayed by the secondary metabolites can underlie the impressive multiplicity of protective functions ranging from toxicity and light/UV shielding to signal transduction (Yang et al., 1997; Grassmann et al., 2002; Hadacek, 2002; Osbourn et al.”
Enhanced production of flavonoids by methyl jasmonate elicitation in cell suspension culture of Hypericum perforatum (2015, background): “A suitable elicitor concentration is important for the cell growth and product yield in plant cell suspension culture process [34].”
Effects of abiotic and biotic elicitors on growth and isoflavonoid accumulation in Pueraria candollei var. candollei and P. candollei var. mirifica cell suspension cultures (2010, background): “It is generally accepted that the production of compounds may relate to the stress level of the cell cultures, including the effectiveness of each elicitor ( Vasconsuelo and Boland 2007 ).”
Engineering secondary metabolite production in hairy roots (2011, background): “Further, molecular mechanism of action of elicitors on secondary metabolism involving signal transduction (not discussed here) has been discussed recently (Angelova et al. 2006; Vasconsuelo and Boland 2007; and Shilpa et al. 2010).”
Elicitors in Plant Tissue Culture (2013, background): “Further on the basis of plant elicitor interaction it may be classified into race specific and general elicitors [3,4] Elicitation of plant cell culture system may be promising as it showed favorable results in fermentation of antibiotics and many other fermented products.”
Elicitation: a stimulation of stress in in vitro plant cell/tissue cultures for enhancement of secondary metabolite production (2017, background): “…the cell line, elicitor concentration, secondary metabolite of interest, type and specificity of elicitors and other conditions including medium composition, contact time and time of addition during a particular cell growth cycle (Wang et al. 2001b; Chong et al. 2005; Vasconsuelo and Boland 2007).”
Secondary metabolites and their multidimensional prospective in plant life (2017, positive): “In view of their current prospective the term secondary metabolite seems inappropriate because it poses them as unimportant despite having a multidimensional role in plant life [6-9] .”