IKKβ phosphorylates p65 at S468 in transactivaton domain 2

By Robert F. Schwabe, H. Sakurai. 2005

83 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/7b2e4b0ba9c522c72244c32f89b4420f5c007990

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. N. Perkins
2. Robert F. Schwabe

In Immunology

1. N. Perkins
2. D. Brenner
3. Robert F. Schwabe

In Oncology

1. N. Perkins
2. Robert F. Schwabe

Citations in the corpus

• Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway (2006, background): “For example, Ser-468 phosphorylation of RelA by IKKb has also been reported to be a cytoplasmic event (Schwabe and Sakurai, 2005) (see below).”
• Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways (2006, background): “IKK- seems not only to be involved in the regulation of I B phosphorylation but also to be the predominant kinase to phosphorylate NF- B subunit p65 in its transactivation domains in hepatocytes and other cell types (28, 31).”
• The Regulation of NF-κB Subunits by Phosphorylation (2016, background): “S468 GSK3β Inhibition [103] IKKε transactivation [104] IKKβ slight inhibition [106]”