Sensitivity advantage of swept source and Fourier domain optical coherence tomography.

By Michael A. Choma, M. Sarunic, Changhuei Yang, J. Izatt. Optics Express, 2003

1,932 citations recorded by the source corpus.

We present theoretical and experimental results which demonstrate the superior sensitivity of swept source (SS) and Fourier domain (FD) optical coherence tomography (OCT) techniques over the conventional time domain (TD) approach. We show that SS- and FD-OCT have equivalent expressions for system signal-to-noise ratio which result in a typical sensitivity advantage of 20-30dB over TD-OCT. Experimental verification is provided using two novel spectral discrimination (SD) OCT systems: a differential fiber-based 800nm FD-OCT system which employs deep-well photodiode arrays, and a differential 1300nm SS-OCT system based on a swept laser with an 87nm tuning range.

Subfields: Biomedical Engineering, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/7af8c1bca1b2c5436e79fb66f4972fea78946cc9

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In Biomedical Engineering

In Radiology, Nuclear Medicine and Imaging

Citations in the corpus

Retinal Imaging and Image Analysis (2010, neutral): “A Fourier transform on the multiwavelength or spectral interferogram is performed to determine the depth of all tissue scatters at the imaged location [41].”
Optical coherence tomography today: speed, contrast, and multimodality (2014, neutral): “Thus, the power Pss associated with the peak value of an A-scan in the case of SS OCT is about N times the power Ptd associated with the A-scan peak of TD OCT.(17) Usually with bandwidth B being same for both TD and SS OCT (17), and N ≥ 1024, a senstitivtiy advantage of ∼20 to 30 dB is obtained for ”
Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography. (2006, background): “For conventional frequencyswept lasers or spectrometer-based OCT systems, a 10 dB or more drop in sensitivity over a 3 mm depth range is typical.[8, 10, 22-25] The superior performance of FDML is the result of quasi-stationary operation.”
Optical coherence tomography angiography (2017, background): “This can be translated into a 50 to 100 times increase in imaging speeds as compared with early time domain detection (Choma et al., 2003; de Boer et al., 2003; Leitgeb et al., 2003a).”
Optical Imaging and Spectroscopy (2009, background): “For this reason, spectral domain OCT is increasingly popular [48,54,148].”
High-speed optical frequency-domain imaging. (2003, neutral): “[20] for OFDR using a swept source.”
Theory, developments and applications of optical coherence tomography (2005, background): “This sensitivity advantage has been investigated theoretically and experimentally in both the FD-OCT and SS-OCT configurations (Choma et al 2003, de Boer et al 2003, Leitgeb et al 2003a).”