High-cost, high-capacity backbone for global brain communication

By Martijn P. van den Heuvel, René S. Kahn, Joaquín Goñi, Olaf Sporns. Proceedings of the National Academy of Sciences of the United States of America, 2012

750 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/7933e817bd7306e286ef1933ead9b9e007a4d8f7

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In Cognitive Neuroscience

In Radiology, Nuclear Medicine and Imaging

Citations in the corpus

Cortical High-Density Counterstream Architectures (2013, background): “Previous studies based on sparse cortical networks have suggested an important structural heterogeneity in the cortex, where hub areas are statistically more interconnected than expected, forming a so-called rich club ( 80 – 82 ) or central core ( 44 ).”
Gradients of structure–function tethering across neocortex (2019, neutral): “Neural elements have a pronounced tendency to form local cliques and tightly-coupled communities with common functional properties [29]; a small proportion of long-distance projections allows signals to be sampled and integrated from these specialized domains [5, 37, 74].”
The Segregation and Integration of Distinct Brain Networks and Their Relationship to Cognition (2016, background): “It is additionally theorized that a highly interconnected group of regions, the “rich club,” is critical for integration across distinct networks (van den Heuvel et al., 2012).”
Toward a computational theory of conscious processing (2013, positive): “Global information sharing and routing would rely on a set of interconnected high-level cortical regions forming a ‘global workspace’ and involving primarily the dorsolateral prefrontal cortex, but also additional hubs in inferior parietal cortex, mid-temporal cortex, and precuneus, and now describe”
Communication dynamics in complex brain networks (2017, background): “For example, most of the shortest paths in a network travel through at least one high-degree node 101 , promoting re-entrant edges (FIG.”
Linking Structure and Function in Macroscale Brain Networks. (2020, positive): “The hubs of the networks are disproportionately interconnected with each other, forming a putative core [11] or ‘rich club’ [12], an architectural feature that potentially allows signals to be sampled and integrated from specialized modules [13].”
Effects of aging on functional and structural brain connectivity☆ (2017, background): “The regions that are part of this structural core and rich club, namely the cingulate gyrus, cuneus, precuneus, superior frontal and parietal lobe, largely overlap with the regions of the default mode network (Cao et al., 2014; Stam, 2010; van den Heuvel et al., 2012).”
Communication Efficiency and Congestion of Signal Traffic in Large-Scale Brain Networks (2014, neutral): “Fuller descriptions of the rich club phenomenon can be found elsewhere, for brain networks in general [15,16], as well as for this particular network [17].”
The role of the posterior cingulate cortex in cognition and disease. (2014, background): “There is surprisingly little neuropsychological research about the cognitive consequences of focal lesions on the PCC. Strokes around the posteromedial cortex produce an amnestic syndrome, which may result in part from damage to both the retrosplenial cortex and PCC (Valenstein et al., 1987).”