CRISPR-mediated adaptive immune systems in bacteria and archaea.

By Rotem Sorek, C. Martin Lawrence, B. Wiedenheft. Annual Review of Biochemistry, 2013

623 citations recorded by the source corpus.

Subfields: Ecology, Endocrinology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/786b95488ed78abf8c5db27d8f2ab038f88e7526

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Ecology

1. Rodolphe Barrangou
2. L. Marraffini
3. Jennifer A. Doudna
4. Feng Zhang
5. Eugene V. Koonin
6. J. van der Oost

In Endocrinology

1. Rodolphe Barrangou
2. L. Marraffini

In Molecular Biology

1. Rodolphe Barrangou
2. L. Marraffini
3. Jennifer A. Doudna
4. Feng Zhang
5. Eugene V. Koonin
6. E. Charpentier
7. P. Hsu
8. J. van der Oost

Citations in the corpus

• CRISPR-Cas systems: prokaryotes upgrade to adaptive immunity (2014, background): “…of 2–3 nt motifs occurring on the 50 end of the protospacer) (Figure 2A) and many type II systems (where they range between 2–5 nt and primarily occur on the 30 endof theprotospacer) (Figure 2B),while they are yet to be characterized in type III systems (Mojica et al., 2009; Sorek et al., 2013).”
• CRISPRDetect: A flexible algorithm to define CRISPR arrays (2016, neutral): “[1–6].”
• Identifying and visualizing functional PAM diversity across CRISPR-Cas systems (2016, methodology): “We also introduced a 4-nt library based on the putative NTTC PAM identified through bioinformatics analysis across type I-C systems (Figure S3D) (Sorek et al., 2013).”