Epigenomic profiling reveals DNA-methylation changes associated with major psychosis.

By J. Mill, Thomas Tang, Z. Kaminsky, Tarang Khare, Simin Yazdanpanah, L. Bouchard, Peixin Jia, A. Assadzadeh, J. Flanagan, A. Schumacher and 2 more. American Journal of Human Genetics, 2008

789 citations recorded by the source corpus.

Subfields: Biological Psychiatry, Molecular Biology, Physiology

View Paper: https://www.semanticscholar.org/paper/77ea44d436bfd7da34afa156618253f8cc339ac8

How researchers see this paper

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In Molecular Biology

1. G. Fan
2. Jonathan Mill
3. Lisa D. Moore
4. Peter M. Visscher
5. Leonard C. Schalkwyk
6. Cristian Coarfa
7. K. Lunnon
8. M. Volta

Citations in the corpus

• DNA methylation profiles in monozygotic and dizygotic twins (2009, methodology): “We validated the microarray findings using sodium bisulfite modification as done previously in our laborator”
• DNA Methylation and Its Basic Function (2013, background): “Furthermore, altered patterns of DNA methylation are observed in psychiatric patients diagnosed with schizophrenia and bipolar disorder (Mill et al, 2008).”
• Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood (2012, background): “The importance of DNA methylation in normal brain function and development is exemplified by the neurodevelopmental deficits associated with mutations in the methyl CpG binding protein 2 gene (MECP2) in Rett syndrome [8], and the aberrant DNA methylation signatures observed in neuropsychiatric disor”