Protein–Protein Interactions Essentials: Key Concepts to Building and Analyzing Interactome Networks

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Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review (2012, methodology): “Ligands often bind to the largest surface cavities of this ensemble (Laskowski et al., 1996; Liang et al., 1998b; Nayal & Honig, 2006).”
Inter-residue, inter-protein and inter-family coevolution: bridging the scales (2017, background): “Systems biologists are primarily interested in the complex networks formed by PPI, with proteins being the nodes, and links indicating interactions between two nodes [1].”