Necrotizing fasciitis: clinical presentation, microbiology, and determinants of mortality.

By S. Schnall. Journal of Bone and Joint Surgery. American volume, 2004

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Necrotizing soft-tissue infection: diagnosis and management. (2007, background): “It is important to emphasize that, although these findings are typical and fairly specific for NSTI, their sensitivity is low, and they are present in only 10%–40% of patients with NSTI [15, 16].”
Necrotizing soft-tissue infections (2011, background): “Bacteroides species are the most common anaerobes involved and are found in more than half of cases, while peptostreptococci are isolated from approximately one-third of patients (16, 17).”
Empiric Antibiotic Treatment Reduces Mortality in Severe Sepsis and Septic Shock From the First Hour: Results From a Guideline-Based Performance Improvement Program* (2014, background): “Other important sepsis treatments have shown time-dependency, like quantitative resuscitation (15) or source control (16).”
The LRINEC (Laboratory Risk Indicator for Necrotizing Fasciitis) score: A tool for distinguishing necrotizing fasciitis from other soft tissue infections* (2004, methodology): “Clinical variables alone are often nonspecific early in the course of the disease and can potentially lead to fatal delay in operative treatment (1, 6, 7).”