Free radical lipid peroxidation: mechanisms and analysis.
By H. Yin, Libin Xu, N. Porter. Chemical Reviews, 2011
1,733 citations recorded by the source corpus.
Subfields: Biochemistry, Nutrition and Dietetics, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/7605ed561e6e14e9d4eff880252c42ef645cfee4
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Citations in the corpus
- Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal (2014, background): “Lipid peroxidation can be described generally as a process under which oxidants such as free radicals or nonradical species attack lipids containing carbon-carbon double bond(s), especially polyunsaturated fatty acids (PUFAs) that involve hydrogen abstraction from a carbon, with oxygen insertion res”
- GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues (2017, neutral): “O bond of PLOOH, the major stable (nonradical) product of the reaction, is, indeed, relatively unstable, driving new initiation reactions by decomposition and producing a plethora of small molecules, most frequently of an electrophilic nature (126).”
- NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis (2019, background): “Lipid peroxidation occurs in three phases: initiation, propagation, and termination (reviewed in detail in [5]).”
- On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death (2017, positive): “9,12,13 The accumulation of cellular LOOH occurs by two primary mechanisms: an iron-catalyzed spontaneous peroxyl radical-mediated process called autoxidation 14,15 and enzyme-mediated processes catalyzed by (non-heme) iron-dependent lipoxyge-nases (LOXs).”
- Insight into the mechanism of ferroptosis inhibition by ferrostatin-1 (2019, background): “LPO of biological membranes encompasses free radical reactions summarized as: i) initiation, beginning with the abstraction by the initiating free radical of a hydrogen atom from a phospholipid containing polyunsaturated fatty acid (PL), leading to a phospholipid carbon centered radical (PL•), and p”
- Lipid Peroxidation and Iron Metabolism: Two Corner Stones in the Homeostasis Control of Ferroptosis (2022, background): “There are a number of reviews of lipid peroxidation that have appeared in last years, particularly related to the biology of lipid oxidation products [14,15].”
- Lipid peroxidation in cell death (2017, background): “9-HPODE rearranges to form an intermediate hemiacetal that can cleave to furnish an aliphatic aldehyde and a b, g-unsaturated aldehyde which can be further oxidized to 4-HPNE [27,30].”
- Ferroptosis: mechanisms and links with diseases (2021, background): “ROS initiate the oxidation of PUFAs and play an important role in non-enzymatic lipid peroxidation or auto-oxidation of lipids.(32) In several arsenic trioxide-resistant human leukemic cell lines, the DHA can enhance the cytotoxic effect of As2O3 through an increase of intracellular lipid peroxidati”