Molecular basis of mechanotransduction in living cells.

By O. Hamill, B. Martinac. Physiological Reviews, 2001

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Cell mechanics: integrating cell responses to mechanical stimuli. (2007, background): “Application of forces to certain cell types promotes intracellular release that may rely in part on calcium-induced calcium release through activation of plasma membrane channels (138), activation of a mechanosensitive phospholipase A2, or a direct physical connection between the ER and plasma membr”
Spatiotemporal feedback between actomyosin and focal-adhesion systems optimizes rapid cell migration. (2006, background): “, 2002), induces conformational changes in proteins to regulate ion channels (Hamill and Martinac, 2001), and uncovers binding sites for adaptor and signaling proteins (Tamada et al.”
MscS‐Like Proteins in Plants (2007, background): “A hallmark of MS ion channels is patch fatigue or adaptation (Hamill and Martinac, 2001).”
How lipids affect the activities of integral membrane proteins. (2004, background): “Because lipid bilayers have a very low compressibility, the volume of the bilayer will not change significantly when the pressure across the bilayer is increased; an osmotic downshift will therefore lead to an increase in membrane area and a decrease in membrane thickness [124].”