The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector.
By R. Screaton, M. Conkright, Y. Katoh, J. Best, G. Canettieri, Shawn Jeffries, Ernesto Guzmán, Sherry L. Niessen, John R. Yates III, H. Takemori and 2 more. Cell, 2004
678 citations recorded by the source corpus.
Subfields: Molecular Biology, Surgery
View Paper: https://www.semanticscholar.org/paper/7577838874b937f84fd6bbccd42f9659bafb99c4
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Citations in the corpus
- GABA-CREB signalling regulates maturation and survival of newly generated neurons in the adult hippocampus (2009, background): “CREB-signaling activity is limited not only by the phosphorylation of CREB but also by the activation of coactivators (Screaton et al., 2004; Ravnskjaer et al., 2007).”
- CREB and the CRTC co-activators: sensors for hormonal and metabolic signals (2011, background): “In high-throughput screens for modulators of a CRE–luciferase reporter, we and others have identified a family of CREB co-activators called CRTC”