Bilayer thickness and membrane protein function: an energetic perspective.

By O. Andersen, R. Koeppe. Annual Review of Biophysics and Biomolecular Structure, 2007

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An Integrated Framework Advancing Membrane Protein Modeling and Design (2015, background): “Effects needed to create the next generation of this model include intrinsic curvature, charge asymmetry [76–78], and variable thickness [79], attributed to the diverse repertoire of lipids that constitute the membrane environment [80].”
Emerging roles for lipids in shaping membrane-protein function (2009, background): “The data demonstrate that the physicochemical properties of the surrounding lipid bilayer result in predictable and stereotyped consequences for channel function in artificial lipid membranes, although the interactions between lipids and membrane proteins have broader significanc”
SYMPOSIUM REVIEW: Lipid microdomains and the regulation of ion channel function (2010, positive): “Raft-enriched lipids such as cholesterol and sphingolipids can also exert effects on channel activity either through direct protein-lipid interactions (Epshtein et al. 2009; Fantini & Barrantes, 2009) or by influencing the physical characteristics of the bilayer (Andersen & Koeppe, 2007).”
Protein Structure Prediction and Design in a Biologically Realistic Implicit Membrane. (2020, neutral): “For future work, we aim to capture membrane deformations (76) through the integration of continuum elastic models (77,78) or hybrid continuum-atomistic models (79).”