ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins.
By Nan Wang, D. Lan, Wengen Chen, F. Matsuura, A. Tall. Proceedings of the National Academy of Sciences of the United States of America, 2004
1,058 citations recorded by the source corpus.
Subfields: Molecular Biology, Oncology, Surgery
View Paper: https://www.semanticscholar.org/paper/7520a35757d12722058708a304304afc69f8ac20
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Citations in the corpus
- Transcriptional integration of metabolism by the nuclear sterol-activated receptors LXR and FXR (2012, background): “ABCG1 promotes cholesterol efflux to HDL, and it is likely that ABCA1 and ABCG1 act in concert to promote cholesterol removal in physiological contexts via HD”
- Cholesterol efflux and atheroprotection: Advancing the concept of reverse cholesterol transport (2012, background): “LCAT enhances cholesterol efflux by ABCG1 (50) and by passive exchange (77).”
- LXR signaling couples sterol metabolism to proliferation in the acquired immune response (2008, background): “ABCG1 is known to play an important role in cholesterol and oxysterol efflux (Kennedy et al., 2005; Terasaka et al., 2007; Wang et al., 2004).”
- Functionally Defective High-Density Lipoprotein: A New Therapeutic Target at the Crossroads of Dyslipidemia, Inflammation, and Atherosclerosis (2006, background): “In addition to ABCA1, there are several other sterolregulated ABC transporters, including ABCG1 and ABCG4, which are involved in cholesterol efflux from macrophages to mature HDL2 and HDL3 particles (Nakamura et al., 2004; Wang et al., 2004; Kennedy et al., 2005).”