Atioxidative protection by melatonin
By R. Hardeland. Endocrine, 2005
651 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Endocrine and Autonomic Systems, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/74542046dfcb73b362c402981aeac804e3349a8f
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In Cellular and Molecular Neuroscience
In Endocrine and Autonomic Systems
In Organic Chemistry
Citations in the corpus
- Melatonin--a pleiotropic, orchestrating regulator molecule. (2011, background): “The toxic metabolite, 5-aminolevulinic acid, is a free radical-generating compound which leads to oxidative stress (Hardeland, 2005).”
- On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK (2013, background): “Regarding their relative antioxidant capacity, AFMK has been reported to be a less effective protector than AMK and melatonin [14, 35, 53].”
- Handbook of the behavioral neurobiology of serotonin (2010, background): “Melatonin is a powerful antioxidant ( Hardeland, 2005 ).”
- Melatonin: an ancient molecule that makes oxygen metabolically tolerable (2015, background): “Besides directly scavenging ROS in these organelles, melatonin may also reduce electron leakage from the respiratory chain complexes [204] which results in higher ATP production [205–207], both of which benefit the cell.”
- One molecule, many derivatives: A never‐ending interaction of melatonin with reactive oxygen and nitrogen species? (2007, background): “AMK, like its precursor melatonin, promotes mitochondrial complex I activity to elevate ATP production by lowering electron leakage and inhibiting opening of the mitochondrial permeability transition pore [151, 152].”
- International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, Classification, and Pharmacology of G Protein-Coupled Melatonin Receptors (2010, background): “AFMK and AMK also form metabolites by interactions with reactive oxygen and nitrogen species (Tan et al., 2007).”
- Melatonin: a well‐documented antioxidant with conditional pro‐oxidant actions (2014, background): “In addition, AMK, like its precursor melatonin, promotes mitochondrial complex I activity to elevate ATP production by lowering electron leakage and inhibiting opening of the mitochondrial permeability transition pore [119, 171, 172].”