Comparative genomic analysis of Lactobacillus rhamnosus GG reveals pili containing a human- mucus binding protein

By M. Kankainen, L. Paulin, S. Tynkkynen, I. von Ossowski, J. Reunanen, P. Partanen, R. Satokari, S. Vesterlund, A. Hendrickx, S. Lebeer and 20 more. Proceedings of the National Academy of Sciences of the United States of America, 2009

739 citations recorded by the source corpus.

Subfields: Food Science, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/739110c011bfc9e5de84c74390d2ef5ef70fa6a8

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Citations in the corpus

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host–microbial interactions (2010, background): “This was recently illustrated by the isolation of an adhesin from the commensal bacteria Lactobaccilus rhamnosus (37).”
Microbes inside—from diversity to function: the case of Akkermansia (2012, background): “Similarly, Lactobacillus rhamnosus GG that is globally marketed as a probiotic (Saxelin, 2008) carries micron-long pili that strongly bind to mucus and may give this strain a competitive advantage while outcompeting pathogens (Kankainen et al., 2009).”
Intestinal microbiota in human health and disease: the impact of probiotics (2011, background): “It was hypothesised that a possible mechanism of the probiotic action of LGG is the stimulation of a stable, even and functionally redundant microbiota and facilitating the colonisation by other beneficial microorganisms (Kankainen et al. 2009).”