Rapid Detection of Carbapenemase-producing Enterobacteriaceae
By P. Nordmann, L. Poirel, L. Dortet. Emerging Infectious Diseases, 2012
802 citations recorded by the source corpus.
To rapidly identify carbapenemase producers in Enterobacteriaceae, we developed the Carba NP test. The test uses isolated bacterial colonies and is based on in vitro hydrolysis of a carbapenem, imipenem. It was 100% sensitive and specific compared with molecular-based techniques. This rapid (<2 hours), inexpensive technique may be implemented in any laboratory.
Subfields: Endocrinology, Molecular Medicine, Pollution
View Paper: https://www.semanticscholar.org/paper/73351776eeea7b95fec2c00d39259c8dee86f671
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Citations in the corpus
- Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods (2016, methodology): “New-Delhi metallo-β-lactamase-producing K. pneumoniae are usually resistant to most β-lactam antibiotics but remain susceptible to aztreonam (Nordmann et al., 2012a).”
- Epidemiology and Diagnostics of Carbapenem Resistance in Gram-negative Bacteria (2019, methodology): “The biochemical assays include the Carba NP [37, 39], its derivative Blue Carba [40], and β Carba [22] tests, which are inexpensive and confirm phenotypically carbapenemase-producing organisms (but not other resistance mechanisms).”
- Carbapenem Resistance: A Review (2017, methodology): “The threat must be answered by strict adherence to infection control strategies and policy guidelines designed for individual countries [75,105].”