Neuropsychiatric symptoms in Alzheimer’s disease
By C. Lyketsos, M. Carrillo, J. Ryan, A. Khachaturian, P. Trzepacz, J. Amatniek, J. Cedarbaum, Robert H. Brashear, David S. Miller. Alzheimer's & Dementia, 2011
1,038 citations recorded by the source corpus.
Neuropsychiatric symptoms (NPS) are core features of Alzheimer's disease and related dementias. Once thought to emerge primarily in people with late‐stage disease, these symptoms are currently known to manifest commonly in very early disease and in prodromal phases, such as mild cognitive impairment. Despite decades of research, reliable treatments for dementia‐associated NPS have not been found, and those that are in widespread use present notable risks for people using these medications. An Alzheimer's Association Research Roundtable was convened in the spring of 2010 to review what is known about NPS in Alzheimer's disease, to discuss classification and underlying neuropathogenesis and vulnerabilities, and to formulate recommendations for new approaches to tailored therapeutics.
Subfields: Pharmacology, Physiology, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/72fc6d509e250d3f897fbcb79598893efc715efc
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In Psychiatry and Mental health
Citations in the corpus
- Neuropsychiatric symptoms as early manifestations of emergent dementia: Provisional diagnostic criteria for mild behavioral impairment (2015, background): “NPS are the noncognitive or behavioral and psychiatric symptoms of dementia and include disturbances of mood, perception, and behavior associated with neurodegenerative disease [1].”