Dendritic cells in cancer immunology and immunotherapy

By S. Wculek, F. J. Cueto, Adriana M. Mujal, I. Melero, M. Krummel, D. Sancho. Nature reviews. Immunology, 2019

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mRNA-based therapeutics: powerful and versatile tools to combat diseases (2022, background): “Tumors boast many mechanisms to evade efficacy immunosurveillance by upregulating immunosuppressive molecules and corresponding cells under the antitumor pressure of immunotherapy, resulting in the induction of peripheral tolerance and central tolerance and significantly impairing immunotherapy effi”
Ferroptosis: mechanisms and links with diseases (2021, background): “Dendritic cells (DCs) appear essential for antitumor immunity via conditioning the tumor microenvironment and regulating priming of antitumor T cells.(186) It has been reported that ALox15-derived lipid peroxide regulates DCs maturation and modulates adaptive immune responses.”
Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives (2021, background): “Interaction between CAFs and dendritic cells (DCs) Tumor-infiltrating dendritic cells (DCs), a heterogeneous group consisting of diverse subpopulations, play a crucial role in the activation and regulation of innate and adaptive immune responses in the TIME through the high expression of class I and”