Computational modelling of the receptor-tyrosine-kinase-activated MAPK pathway.

By Richard J. Orton, Oliver E. Sturm, Vladislav Vyshemirsky, Muffy Calder, David R. Gilbert, Walter Kolch. Biochemical Journal, 2005

376 citations recorded by the source corpus.

Subfields: Modeling and Simulation, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/728bcdf16dd2bc919e6049fed82b662411585c30

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Modeling and Simulation

1. Y. Yarden

In Molecular Biology

1. S. Hagan
2. Walter Kolch
3. Oliver Rath
4. A. Citri
5. Y. Yarden
6. A. Dhillon
7. M. Lacouture
8. C. Hill

Citations in the corpus

• EGF–ERBB signalling: towards the systems level (2006, background): “Recent coherent reviews describe the process of modelling biological system”
• MAP kinase signalling pathways in cancer (2007, background): “Indeed mathematical modelling predicts that Ras and Raf activation are very sensitive points of regulation that can determine the overall activation profile (Orton et al., 2005).”
• Rule-Based Modelling of Cellular Signalling (2007, neutral): “A large majority of models aimed at investigating the behavior of biological pathways are cast in terms of systems of differential equations [11,12,13,14,15,16].”