Faculty Opinions recommendation of Integrin beta cytoplasmic domain interactions with phosphotyrosine-binding domains: a structural prototype for diversity in integrin signaling.

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Structural basis of integrin activation by talin. (2007, background): “Several other PTB domains bind to b3 in a similar fashion to talin (Calderwood et al., 2003; Garcia-Alvarez et al., 2003), but only talin has exhibited the capacity to activate integrins.”
Integrin Structure and Function (2010, background): “The membrane proximal NpxY motif is required for the binding of the cytoskeletal protein talin (Calderwood et al. 2003).”